I've turned this over in my head quite a bit.. I like the look of the X4S but the roll up takes up some space and I'd rather not have a vinyl truck cover again. I think the Leer HF650M will be my selection.
Are the ceiling or walls finished? Exposed studs will be easier for a contractor to review. Find a general contractor who can handle the complete job or you need a framer first, a garage door company second (not Lowes or Home Depot, check the yellow pages) and a siding guy.
Might be cheaper...
I was considering a skid plate system but with a PowerBoost I might just have to make one for myself.
https://rcimetalworks.com/product-category/ford/ford-f-150/15-22-f-150/